FUNCTIONAL ANALYSIS OF VARIANTS IN COMPLEMENT FACTOR I IDENTIFIED IN AGE-RELATED MACULAR DEGENERATION AND ATYPICAL HEMOLYTIC UREMIC SYNDROME

Functional Analysis of Variants in Complement Factor I Identified in Age-Related Macular Degeneration and Atypical Hemolytic Uremic Syndrome

Complement factor I (FI) is a central inhibitor of the complement system, and impaired FI function increases complement activation, contributing to diseases such as age-related macular degeneration (AMD) and atypical hemolytic uremic syndrome (aHUS).Genetic variation in complement factor Body Cleanser I (CFI) has been identified in both AMD and aHU

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Investigating the Principles of Indigenous Housing Architecture of Hot and Dry Climate of Iran with the Formal Impact Approach of the Building in Promoting Thermal Comfort of Building Users

The study of architectural principles in various regions indicates the close relationship Gift Box Set between the common architecture in each region and its geographical environment.Scrutinizing the characteristics of architectural styles in different regions and their merits can be effective in providing optimal architectural patterns.Indigenous

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Silibinin inhibits PM2.5-induced liver triglyceride accumulation through enhancing the function of mitochondrial Complexes I and II

BackgroundThe standardized extract of milk thistle seeds, known as silibinin, has been utilized in herbal medicine for over two centuries, with the aim of safeguarding the liver against the deleterious effects of various toxic substances.However, Services the role of silibinin in Particulate Matter (PM2.5)-induced intrahepatic triglyceride accumula

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Ethnic differences in guideline-indicated statin initiation for people with type 2 diabetes in UK primary care, 2006-2019: A cohort study.

BackgroundType 2 diabetes is 2-3 times more prevalent in people of South Asian and African/African Caribbean ethnicity than people of European ethnicity living Tabletop Decor in the UK.The former 2 groups also experience excess atherosclerotic cardiovascular disease (ASCVD) complications of diabetes.We aimed to study ethnic differences in statin in

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